London June 3 (IANS) An experimental new treatment for ovarian cancer led to a dramatic shrinking of tumours in a small early-phase study the media reported on Saturday.
Researchers from the Institute of Cancer Research and the Royal Marsden NHS Foundation Trust in London were testing a drug known as ONX-0801 for safety but found that tumours in half of the 15 women studied shrank during the trial a response they called highly unusual and very promising reports the Guardian.
The drug mimics folic acid to attack ovarian cancer cells.
Researchers believe the drug could hold promise for women whose ovarian cancer has stopped responding to traditional treatment.
Additionally because the drug specifically targeted cancer cells it did not show the side effects typically associated with chemotherapy such as infections diarrhoea nerve damage and hair loss.
The results we have seen in this trial are very promising the Guardian quoted Udai Banerji the leader of the study and deputy director of the drug development unit at the Institute of Cancer Research as saying.
It is rare to see such clear evidence of reproducible responses in these early stages of drug development.
However Banerji warned that the treatment is still in its trial stage.
The five-year survival rate for all ovarian cancers is 45 per cent.
Between 2008 and 2010 in England 36 per cent of the more than 14 000 women diagnosed with ovarian cancer died in the first year. More than 1 600 died in the first month according to Pubic Health England.
--IANS
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Experimental ovarian cancer treatment promising , say researchers
