The 52-year-old actress and Clooney portrayed nurse Carol Hathaway and Dr. Doug Ross respectively on the show.
Margulies recalled a moment when the actor shut down an upset guest star on the set of the medical drama reports etonline.com.
"I remember it was a guest star who was I don t know they were upset and they were keeping all of us waiting in the trailer.
"And we were all on set waiting and when they came on I was just watching and George said You know you keep all of us waiting. The crew actually doesn t get to go home to see their families. So that s what that little tantrum was .
"And I was like Nice! It never happened again " Margulies said at the American Film Institute s Life Achievement Award gala which honoured Clooney earlier this week.
"The Good Wife" star said that she was "very very lucky" to have been able to work with Clooney.
--IANS ks/nn/