New York Oct 24 (IANS) Children who receive higher levels of Vitamin D during infancy and childhood may be significantly at a lower risk of developing islet autoimmunity as well as Type 1 diabetes according to a study.
Type 1 diabetes is a chronic autoimmune disease that is increasing by 3-5 per cent annually worldwide and occurs when the body s immune system destroys its own insulin-producing beta cells in the pancreas.
Islet autoimmunity detected by antibodies that appear when the immune system attacks the islet cells in the pancreas that produce insulin is a precursor to Type 1 diabetes.
Vitamin D represents a candidate protective factor for Type 1 diabetes as it regulates the immune system and autoimmunity the researchers said.
"For several years there has been controversy among scientists about whether Vitamin D lowers the risk of developing of islet autoimmunity and Type 1 diabetes " said lead author Jill Norris from the Colorado University - Anschutz.
In the study published in the journal Diabetes the team searched for triggers and protective factors in 8 676 children with elevated Type 1 diabetes risk.
They identified islet autoimmunity in 376 children and compared them with 1 041 children who did not.
Among children who were at an increased genetic risk for Type 1 diabetes those with lower Vitamin D levels in infancy and childhood went on to develop islet autoimmunity compared with those who did not develop autoimmunity.
The study showed that higher childhood vitamin D levels are significantly associated with a decreased risk of islet autoimmunity.
--IANS
rt/amit
